{"id":927,"date":"2026-07-31T11:01:49","date_gmt":"2026-07-31T11:01:49","guid":{"rendered":"http:\/\/avenuemedispa.co.uk\/?post_type=project&#038;p=927"},"modified":"2026-07-31T11:31:16","modified_gmt":"2026-07-31T11:31:16","slug":"polynucleotide","status":"publish","type":"project","link":"https:\/\/avenuemedispa.co.uk\/index.php\/project\/polynucleotide\/","title":{"rendered":"Polynucleotides"},"content":{"rendered":"\n[et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;section&#8221; _builder_version=&#8221;4.27.6&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;2_3,1_3&#8243; admin_label=&#8221;row&#8221; _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;2_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text admin_label=&#8221;Text&#8221; _builder_version=&#8221;4.27.6&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; use_border_color=&#8221;off&#8221; border_color=&#8221;#ffffff&#8221; border_style=&#8221;solid&#8221; global_colors_info=&#8221;{}&#8221;]<h1>Polynucleotide Treatments<\/h1>\n<h3>Naturally Regenerate, Repair &amp; Rejuvenate Your Skin<\/h3>[\/et_pb_text][et_pb_image src=&#8221;https:\/\/avenuemedispa.co.uk\/wp-content\/uploads\/2026\/07\/Screenshot-2026-07-31-at-12.05.55.png&#8221; _builder_version=&#8221;4.27.6&#8243; _module_preset=&#8221;default&#8221; alt=&#8221;Polynucleotide&#8221; title_text=&#8221;Polynucleotide&#8221; hover_enabled=&#8221;0&#8243; sticky_enabled=&#8221;0&#8243;][\/et_pb_image][et_pb_text admin_label=&#8221;Text&#8221; _builder_version=&#8221;4.27.6&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; hover_enabled=&#8221;0&#8243; use_border_color=&#8221;off&#8221; border_color=&#8221;#ffffff&#8221; border_style=&#8221;solid&#8221; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<p class=\"isSelectedEnd\"><span>At Avenue Medispa, we offer the latest generation of regenerative injectable treatments designed to improve skin quality from within. <strong>Polynucleotides<\/strong> are one of the most exciting advances in aesthetic medicine, stimulating your skin&#8217;s natural repair processes to restore hydration, elasticity and radiance without changing your natural facial features.<\/span><\/p>\n<p class=\"isSelectedEnd\"><span>Unlike traditional dermal fillers, polynucleotides work by encouraging your body to regenerate healthy skin tissue. The result is smoother, firmer, healthier-looking skin that continues to improve over the weeks following treatment.<\/span><\/p>\n<p class=\"isSelectedEnd\"><span>Our experienced medical practitioners offer three advanced treatments tailored to different concerns:<\/span><\/p>\n<ul data-spread=\"false\">\n<li><strong><span>PLINEST\u00ae<\/span><\/strong><span> \u2013 Skin regeneration for the face, neck and d\u00e9colletage.<\/span><\/li>\n<li><strong><span>PLINEST\u00ae Eye<\/span><\/strong><span> \u2013 Specifically formulated for the delicate eye area.<\/span><\/li>\n<li><strong><span>Newest\u00ae<\/span><\/strong><span> \u2013 An innovative treatment combining polynucleotides with hyaluronic acid for enhanced skin hydration and rejuvenation.<\/span><\/li>\n<\/ul>\n<h2><span><\/span><\/h2>\n<h2><span>What Are Polynucleotides?<\/span><\/h2>\n<p class=\"isSelectedEnd\"><span>Polynucleotides are highly purified DNA fragments that help stimulate the skin&#8217;s natural healing and regeneration processes. They encourage fibroblasts to produce new collagen and elastin, improve skin hydration and elasticity, reduce inflammation and protect cells from oxidative stress.<\/span><\/p>\n<p class=\"isSelectedEnd\"><span>Rather than simply filling lines or adding volume, polynucleotides improve the overall health and quality of the skin, making them ideal for patients seeking natural-looking rejuvenation.<\/span><\/p>\n<p class=\"isSelectedEnd\"><span><\/span><\/p>\n<h3><span>Benefits include:<\/span><\/h3>\n<ul data-spread=\"false\">\n<li><span>Improves skin texture and tone<\/span><\/li>\n<li><span>Stimulates collagen and elastin production<\/span><\/li>\n<li><span>Deeply hydrates the skin<\/span><\/li>\n<li><span>Reduces fine lines and crepey skin<\/span><\/li>\n<li><span>Improves skin firmness and elasticity<\/span><\/li>\n<li><span>Brightens tired, dull complexions<\/span><\/li>\n<li><span>Supports tissue repair<\/span><\/li>\n<li><span>Provides subtle, natural rejuvenation<\/span><\/li>\n<\/ul>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.27.6&#8243; _module_preset=&#8221;default&#8221; hover_enabled=&#8221;0&#8243; sticky_enabled=&#8221;0&#8243;]<h1><span>PLINEST\u00ae<\/span><\/h1>\n<h2><span>Regenerative Skin Rejuvenation<\/span><\/h2>\n<p><span>PLINEST\u00ae is an advanced injectable polynucleotide treatment designed to improve skin quality by stimulating natural tissue regeneration.<\/span><\/p>\n<p><span>It is ideal for treating:<\/span><\/p>\n<ul data-spread=\"false\">\n<li><span>Face<\/span><\/li>\n<li><span>Neck<\/span><\/li>\n<li><span>D\u00e9colletage<\/span><\/li>\n<li><span>Hands<\/span><\/li>\n<\/ul>\n<p><span>PLINEST\u00ae is perfect for patients noticing early signs of ageing, loss of elasticity or dull, tired skin. Following treatment, collagen production increases gradually, leaving the skin smoother, firmer and healthier over the following weeks.<\/span><\/p>\n<p><span><\/span><\/p>\n<h3><span>Ideal for treating:<\/span><\/h3>\n<ul data-spread=\"false\">\n<li><span>Fine lines<\/span><\/li>\n<li><span>Sun-damaged skin<\/span><\/li>\n<li><span>Loss of elasticity<\/span><\/li>\n<li><span>Rough skin texture<\/span><\/li>\n<li><span>Ageing skin<\/span><\/li>\n<li><span>Acne scarring<\/span><\/li>\n<\/ul>\n<div contenteditable=\"false\"><hr \/><\/div>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.27.6&#8243; _module_preset=&#8221;default&#8221; hover_enabled=&#8221;0&#8243; sticky_enabled=&#8221;0&#8243;]<h1><span>PLINEST\u00ae Eye<\/span><\/h1>\n<h2><span>Targeted Rejuvenation for the Eye Area<\/span><\/h2>\n<p class=\"isSelectedEnd\"><span>The skin around the eyes is thinner and more delicate than anywhere else on the face, making it one of the first areas to show signs of ageing.<\/span><\/p>\n<p class=\"isSelectedEnd\"><span>PLINEST\u00ae Eye has been specially developed to treat this delicate area by improving skin quality without adding unwanted volume.<\/span><\/p>\n<p class=\"isSelectedEnd\"><span>It can help improve:<\/span><\/p>\n<ul data-spread=\"false\">\n<li><span>Fine lines and crow&#8217;s feet<\/span><\/li>\n<li><span>Crepey eyelid skin<\/span><\/li>\n<li><span>Dark circles<\/span><\/li>\n<li><span>Thin, fragile skin<\/span><\/li>\n<li><span>Loss of firmness<\/span><\/li>\n<li><span>Tired-looking eyes<\/span><\/li>\n<\/ul>\n<p><span>The result is brighter, smoother and more youthful-looking eyes with completely natural results.<\/span><\/p>[\/et_pb_text][et_pb_divider _builder_version=&#8221;4.27.6&#8243; _module_preset=&#8221;default&#8221; hover_enabled=&#8221;0&#8243; sticky_enabled=&#8221;0&#8243;][\/et_pb_divider][et_pb_text _builder_version=&#8221;4.27.6&#8243; _module_preset=&#8221;default&#8221; hover_enabled=&#8221;0&#8243; sticky_enabled=&#8221;0&#8243;]<h1><span>Newest\u00ae<\/span><\/h1>\n<h2><span>Polynucleotides Plus Hyaluronic Acid<\/span><\/h2>\n<p class=\"isSelectedEnd\"><span>Newest\u00ae combines the regenerative power of polynucleotides with the intense hydration provided by hyaluronic acid.<\/span><\/p>\n<p class=\"isSelectedEnd\"><span>This dual-action treatment repairs skin while simultaneously restoring moisture levels, making it ideal for patients experiencing dehydrated, ageing or environmentally damaged skin.<\/span><\/p>\n<p class=\"isSelectedEnd\"><span>Benefits include:<\/span><\/p>\n<ul data-spread=\"false\">\n<li><span>Deep skin hydration<\/span><\/li>\n<li><span>Improved elasticity<\/span><\/li>\n<li><span>Increased collagen production<\/span><\/li>\n<li><span>Enhanced skin glow<\/span><\/li>\n<li><span>Smoother texture<\/span><\/li>\n<li><span>Reduction in fine lines<\/span><\/li>\n<li><span>Long-lasting skin rejuvenation<\/span><\/li>\n<\/ul>\n<p><span>Newest\u00ae is particularly popular for patients wanting healthier, radiant skin with improved hydration and luminosity.<\/span><\/p>[\/et_pb_text][et_pb_divider _builder_version=&#8221;4.27.6&#8243; _module_preset=&#8221;default&#8221; hover_enabled=&#8221;0&#8243; sticky_enabled=&#8221;0&#8243;][\/et_pb_divider][et_pb_text _builder_version=&#8221;4.27.6&#8243; _module_preset=&#8221;default&#8221; hover_enabled=&#8221;0&#8243; sticky_enabled=&#8221;0&#8243;]<h1><span>How Many Treatments Will I Need?<\/span><\/h1>\n<p class=\"isSelectedEnd\"><span>For optimal results we generally recommend:<\/span><\/p>\n<ul data-spread=\"false\">\n<li><span>An initial course of 3 treatments<\/span><\/li>\n<li><span>Treatments spaced 2\u20134 weeks apart<\/span><\/li>\n<li><span>Maintenance treatments every 6\u20139 months depending on your skin concerns<\/span><\/li>\n<\/ul>\n<p class=\"isSelectedEnd\"><span>Your practitioner will create a personalised treatment plan during your consultation.<\/span><\/p>\n<p class=\"isSelectedEnd\"><span><\/span><\/p>\n<h1><span>Are Polynucleotides Right for Me?<\/span><\/h1>\n<p class=\"isSelectedEnd\"><span>Polynucleotide treatments are suitable for both men and women looking to improve skin quality naturally.<\/span><\/p>\n<p class=\"isSelectedEnd\"><span>They are ideal if you want to:<\/span><\/p>\n<ul data-spread=\"false\">\n<li><span>Prevent early signs of ageing<\/span><\/li>\n<li><span>Improve skin health<\/span><\/li>\n<li><span>Restore hydration<\/span><\/li>\n<li><span>Reduce fine lines<\/span><\/li>\n<li><span>Brighten tired skin<\/span><\/li>\n<li><span>Enhance your results alongside other aesthetic treatments<\/span><\/li>\n<\/ul>\n<p><span>During your consultation, we&#8217;ll assess your skin and recommend the treatment most suitable for your concerns.<\/span><\/p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_pricing_tables admin_label=&#8221;Pricing Tables&#8221; _builder_version=&#8221;4.27.6&#8243; link_option_url=&#8221;https:\/\/www.phorest.com\/salon\/avenuemedispalimited&#8221; hover_enabled=&#8221;0&#8243; use_border_color=&#8221;off&#8221; border_color=&#8221;#ffffff&#8221; border_style=&#8221;solid&#8221; button_letter_spacing_hover=&#8221;0&#8243; remove_featured_drop_shadow=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; button_text_size__hover_enabled=&#8221;off&#8221; button_one_text_size__hover_enabled=&#8221;off&#8221; button_two_text_size__hover_enabled=&#8221;off&#8221; button_text_color__hover_enabled=&#8221;off&#8221; button_one_text_color__hover_enabled=&#8221;off&#8221; button_two_text_color__hover_enabled=&#8221;off&#8221; button_border_width__hover_enabled=&#8221;off&#8221; button_one_border_width__hover_enabled=&#8221;off&#8221; button_two_border_width__hover_enabled=&#8221;off&#8221; button_border_color__hover_enabled=&#8221;off&#8221; button_one_border_color__hover_enabled=&#8221;off&#8221; button_two_border_color__hover_enabled=&#8221;off&#8221; button_border_radius__hover_enabled=&#8221;off&#8221; button_one_border_radius__hover_enabled=&#8221;off&#8221; button_two_border_radius__hover_enabled=&#8221;off&#8221; button_letter_spacing__hover_enabled=&#8221;on&#8221; button_letter_spacing__hover=&#8221;0&#8243; button_one_letter_spacing__hover_enabled=&#8221;off&#8221; button_two_letter_spacing__hover_enabled=&#8221;off&#8221; button_bg_color__hover_enabled=&#8221;off&#8221; button_one_bg_color__hover_enabled=&#8221;off&#8221; button_two_bg_color__hover_enabled=&#8221;off&#8221; sticky_enabled=&#8221;0&#8243;][et_pb_pricing_table featured=&#8221;on&#8221; title=&#8221;PLINEST\u00ae Polynucleotide Treatment&#8221; subtitle=&#8221;Regenerative Skin Rejuvenation&#8221; currency=&#8221;\u00a3&#8221; per=&#8221;Single Treatment&#8221; sum=&#8221;250&#8243; button_url=&#8221;https:\/\/www.phorest.com\/salon\/avenuemedispalimited&#8221; button_text=&#8221;Book here&#8221; _builder_version=&#8221;4.27.6&#8243; _module_preset=&#8221;default&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_transition=&#8221;on&#8221; sticky_enabled=&#8221;0&#8243;]<p class=\"isSelectedEnd\"><span>PLINEST\u00ae is an advanced injectable polynucleotide treatment designed to improve skin quality by stimulating natural tissue regeneration. Ideal for face, neck, hands and decolletage.<\/span><span><\/span><\/p>\n<p class=\"isSelectedEnd\"><span>For optimal results we generally suggest a course of 2 &#8211; 3 treatments.<\/span><\/p>[\/et_pb_pricing_table][et_pb_pricing_table title=&#8221;PLINEST\u00ae Eye&#8221; subtitle=&#8221;Targeted Rejuvenation for the Eye Area&#8221; currency=&#8221;\u00a3&#8221; per=&#8221;Single Treatment&#8221; sum=&#8221;250&#8243; button_url=&#8221;https:\/\/www.phorest.com\/salon\/avenuemedispalimited&#8221; button_text=&#8221;Book here&#8221; _builder_version=&#8221;4.27.6&#8243; header_font=&#8221;||||&#8221; body_font=&#8221;||||&#8221; subheader_font=&#8221;||||&#8221; price_font=&#8221;||||&#8221; currency_frequency_font=&#8221;||||&#8221; button_icon_placement=&#8221;right&#8221; button_on_hover=&#8221;on&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; button_text_size__hover_enabled=&#8221;off&#8221; button_one_text_size__hover_enabled=&#8221;off&#8221; button_two_text_size__hover_enabled=&#8221;off&#8221; button_text_color__hover_enabled=&#8221;off&#8221; button_one_text_color__hover_enabled=&#8221;off&#8221; button_two_text_color__hover_enabled=&#8221;off&#8221; button_border_width__hover_enabled=&#8221;off&#8221; button_one_border_width__hover_enabled=&#8221;off&#8221; button_two_border_width__hover_enabled=&#8221;off&#8221; button_border_color__hover_enabled=&#8221;off&#8221; button_one_border_color__hover_enabled=&#8221;off&#8221; button_two_border_color__hover_enabled=&#8221;off&#8221; button_border_radius__hover_enabled=&#8221;off&#8221; button_one_border_radius__hover_enabled=&#8221;off&#8221; button_two_border_radius__hover_enabled=&#8221;off&#8221; button_letter_spacing__hover_enabled=&#8221;off&#8221; button_one_letter_spacing__hover_enabled=&#8221;off&#8221; button_two_letter_spacing__hover_enabled=&#8221;off&#8221; button_bg_color__hover_enabled=&#8221;off&#8221; button_one_bg_color__hover_enabled=&#8221;off&#8221; button_two_bg_color__hover_enabled=&#8221;off&#8221; sticky_transition=&#8221;on&#8221; sticky_enabled=&#8221;0&#8243;]<p>PLINEST\u00ae Eye has been specially developed to treat this delicate area by improving skin quality without adding unwanted volume.<\/p>[\/et_pb_pricing_table][et_pb_pricing_table title=&#8221;Newest\u00ae&#8221; subtitle=&#8221;Polynucleotides Plus Hyaluronic Acid&#8221; currency=&#8221;\u00a3&#8221; per=&#8221;single treatment&#8221; sum=&#8221;250&#8243; button_url=&#8221;https:\/\/www.phorest.com\/salon\/avenuemedispalimited&#8221; button_text=&#8221;Book here&#8221; _builder_version=&#8221;4.27.6&#8243; _module_preset=&#8221;default&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_transition=&#8221;on&#8221; sticky_enabled=&#8221;0&#8243;]<p class=\"isSelectedEnd\"><span>Newest\u00ae combines the regenerative power of polynucleotides with the intense hydration provided by hyaluronic acid.<\/span><\/p>\n<p><span>This dual-action treatment repairs skin while simultaneously restoring moisture levels, making it ideal for patients experiencing dehydrated, ageing or environmentally damaged skin.<\/span><\/p>[\/et_pb_pricing_table][\/et_pb_pricing_tables][et_pb_cta title=&#8221;What to Expect&#8221; button_url=&#8221;https:\/\/www.phorest.com\/salon\/avenuemedispalimited&#8221; button_text=&#8221;Book a treatment&#8221; admin_label=&#8221;Call To Action&#8221; _builder_version=&#8221;4.27.6&#8243; header_text_align=&#8221;center&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; button_alignment=&#8221;center&#8221; hover_enabled=&#8221;0&#8243; use_border_color=&#8221;off&#8221; border_color=&#8221;#ffffff&#8221; border_style=&#8221;solid&#8221; button_letter_spacing_hover=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; button_text_size__hover_enabled=&#8221;off&#8221; button_one_text_size__hover_enabled=&#8221;off&#8221; button_two_text_size__hover_enabled=&#8221;off&#8221; button_text_color__hover_enabled=&#8221;off&#8221; button_one_text_color__hover_enabled=&#8221;off&#8221; button_two_text_color__hover_enabled=&#8221;off&#8221; button_border_width__hover_enabled=&#8221;off&#8221; button_one_border_width__hover_enabled=&#8221;off&#8221; button_two_border_width__hover_enabled=&#8221;off&#8221; button_border_color__hover_enabled=&#8221;off&#8221; button_one_border_color__hover_enabled=&#8221;off&#8221; button_two_border_color__hover_enabled=&#8221;off&#8221; button_border_radius__hover_enabled=&#8221;off&#8221; button_one_border_radius__hover_enabled=&#8221;off&#8221; button_two_border_radius__hover_enabled=&#8221;off&#8221; button_letter_spacing__hover_enabled=&#8221;on&#8221; button_letter_spacing__hover=&#8221;0&#8243; button_one_letter_spacing__hover_enabled=&#8221;off&#8221; button_two_letter_spacing__hover_enabled=&#8221;off&#8221; button_bg_color__hover_enabled=&#8221;off&#8221; button_one_bg_color__hover_enabled=&#8221;off&#8221; button_two_bg_color__hover_enabled=&#8221;off&#8221; sticky_enabled=&#8221;0&#8243; locked=&#8221;off&#8221;]<p class=\"isSelectedEnd\"><span>Treatment takes approximately 30\u201345 minutes.<\/span><\/p>\n<p class=\"isSelectedEnd\"><span>A topical anaesthetic can be applied to maximise comfort before a series of tiny injections are placed into the treatment area.<\/span><\/p>\n<p><span>Most patients experience minimal downtime. Mild redness, swelling or small injection marks may occur for 24\u201348 hours before settling naturally.<\/span><\/p>[\/et_pb_cta][\/et_pb_column][\/et_pb_row][\/et_pb_section]\n","protected":false},"excerpt":{"rendered":"<p>Polynucleotide Treatments Naturally Regenerate, Repair &amp; Rejuvenate Your SkinAt Avenue Medispa, we offer the latest generation of regenerative injectable treatments designed to improve skin quality from within. Polynucleotides are one of the most exciting advances in aesthetic medicine, stimulating your skin&#8217;s natural repair processes to restore hydration, elasticity and radiance without changing your natural facial [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"project_category":[6,7],"project_tag":[],"class_list":["post-927","project","type-project","status-publish","hentry","project_category-facial-aesthetics","project_category-facial-treatments"],"_links":{"self":[{"href":"https:\/\/avenuemedispa.co.uk\/index.php\/wp-json\/wp\/v2\/project\/927","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/avenuemedispa.co.uk\/index.php\/wp-json\/wp\/v2\/project"}],"about":[{"href":"https:\/\/avenuemedispa.co.uk\/index.php\/wp-json\/wp\/v2\/types\/project"}],"author":[{"embeddable":true,"href":"https:\/\/avenuemedispa.co.uk\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/avenuemedispa.co.uk\/index.php\/wp-json\/wp\/v2\/comments?post=927"}],"version-history":[{"count":8,"href":"https:\/\/avenuemedispa.co.uk\/index.php\/wp-json\/wp\/v2\/project\/927\/revisions"}],"predecessor-version":[{"id":2085,"href":"https:\/\/avenuemedispa.co.uk\/index.php\/wp-json\/wp\/v2\/project\/927\/revisions\/2085"}],"wp:attachment":[{"href":"https:\/\/avenuemedispa.co.uk\/index.php\/wp-json\/wp\/v2\/media?parent=927"}],"wp:term":[{"taxonomy":"project_category","embeddable":true,"href":"https:\/\/avenuemedispa.co.uk\/index.php\/wp-json\/wp\/v2\/project_category?post=927"},{"taxonomy":"project_tag","embeddable":true,"href":"https:\/\/avenuemedispa.co.uk\/index.php\/wp-json\/wp\/v2\/project_tag?post=927"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}